Troponin domain superfamily

Definition

The troponin (Tn) complex regulates Ca2+induced muscle contraction. Tn contains three subunits, Ca2+binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). This entry includes domains from troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin [[cite:PMID:3102969], [cite:PMID:7852318], [cite:PMID:7601340]]. Structurally this domain forms a heterodimeric coiled coil.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• TNNI1
• TNNI2
• TNNI3
• TNNT1
• TNNT2
• TNNT3