DAZ, RNA recognition motif, vertebrates

Definition

This entry represents the RRM of DAZ proteins from vertebrates. DAZ family members include BOULE, DAZ-Like (DAZL) and DAZ. They are found almost exclusively in germ cells and are key players for germ cell development [[cite:PMID:26327816], [cite:PMID:19865085]]. They contain a highly conserved RNA-binding motif (RNA recognition motif; RRM) and a unique DAZ repeat PMID:15139965. Their RRM has been shown to bind 3'-UTR sequences of target mRNAs. They may be involved in regulation of mRNA translation PMID:26327816.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• DAZ1
• DAZ2
• DAZ3
• DAZ4
• DAZL