Seroatlas · Human Serome Atlas

UNQ6493/PRO21345

Putative uncharacterized protein UNQ6493/PRO21345

Also known as: YS001_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6UXR8
Gene: UNQ6493/PRO21345
Canonical length: 122 aa

OverviewNCBI Gene

No narrative summary is available for UNQ6493/PRO21345 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

122 residues, UniProt reviewed canonical sequence.

>Q6UXR8|UNQ6493/PRO21345
     1  MEPWWPRGTG ANAPWVLVAV PPGLFPSLLG ACCTLTSSSW LQPRFWGLGW RVEVGLEGAG
    61  GSSQNYQAAL PSFFCLAASP ASRPAIFGIL AAEPPSASPQ APWPKPGCAS PHGSHWPSIL
   121  IC

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against UNQ6493/PRO21345 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.38

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads UNQ6493/PRO21345 as an antibody target. Whether an autoantibody or antibody against UNQ6493/PRO21345 could matter depends on whether native UNQ6493/PRO21345 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

UNQ6493/PRO21345 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label UNQ6493/PRO21345 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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