Seroatlas · Human Serome Atlas

UNQ6494/PRO21346

Putative uncharacterized protein UNQ6494/PRO21346

Also known as: YI004_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6UXR6
Gene: UNQ6494/PRO21346
Canonical length: 183 aa

OverviewNCBI Gene

No narrative summary is available for UNQ6494/PRO21346 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

183 residues, UniProt reviewed canonical sequence.

>Q6UXR6|UNQ6494/PRO21346
     1  MQCWQQPFLR FLQQPFFLAT ASLAGSSSSF NVLIPKRDED GDGEGPGDVT AGVSRAAGSP
    61  SGWEAPWVQQ PRCCRRATPV CCAGQGPPRS LQQGGSEVLL GQLCSPEPDW LPSSGPKVAK
   121  QVFQVAAELL QHPEHFVPSS VPEGCVHKPG STCDGSLKGR AYPSCVPKRD PEHSREESHP
   181  LSG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against UNQ6494/PRO21346 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.59

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads UNQ6494/PRO21346 as an antibody target. Whether an autoantibody or antibody against UNQ6494/PRO21346 could matter depends on whether native UNQ6494/PRO21346 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

UNQ6494/PRO21346 is annotated as secreted, so native UNQ6494/PRO21346 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label UNQ6494/PRO21346 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...