Seroatlas · Human Serome Atlas

UNQ6190/PRO20217

Putative uncharacterized protein UNQ6190/PRO20217

Also known as: YO002_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6UXQ8
Gene: UNQ6190/PRO20217
Canonical length: 127 aa

OverviewNCBI Gene

No narrative summary is available for UNQ6190/PRO20217 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

127 residues, UniProt reviewed canonical sequence.

>Q6UXQ8|UNQ6190/PRO20217
     1  MAGVRARAPL PLALLLSLPA APGGRDPSAS RARFPQRLGR APCFEVGLRK PPPPPLLSPP
    61  SFSSGSSRPL QRPRGPKDGA GRKVCAKLVK RLPGESGSCE DGQSAPAQPP RRRTGTRACP
   121  PRAPLWR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against UNQ6190/PRO20217 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.75

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads UNQ6190/PRO20217 as an antibody target. Whether an autoantibody or antibody against UNQ6190/PRO20217 could matter depends on whether native UNQ6190/PRO20217 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

UNQ6190/PRO20217 is annotated as secreted, so native UNQ6190/PRO20217 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label UNQ6190/PRO20217 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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