ZNF892
Zinc finger protein 892
Also known as: ZN892_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- A0A087WUV0
- Gene
- ZNF892
- Canonical length
- 522 aa
OverviewNCBI Gene
No narrative summary is available for ZNF892 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
522 residues, UniProt reviewed canonical sequence.
>A0A087WUV0|ZNF892
1 MEPEGRGSLF EDSDLLHAGN PKENDVTAVL LTPGSQELMI RDMAEALTQW RQLNSPQGDV
61 PEKPRNLVLL GLPISTPDVI SQLEHEEELE REVSKAASQK HWETIPESKE LTPEKDISEE
121 ESAPGVLIVR FSKESSSECE DSLESQQENH EKHLIQEAVT EKSSRERSYQ SDEFRRNCTQ
181 RSLLVQQQGE RLHHCDSFKN NLKQNSDIIR HERICAGKKP WKCNECEKAF SYYSAFVLHQ
241 RIHTGEKPYE CNECGKAFSQ SIHLTLHQRI HTGEKPYECH ECGKAFSHRS ALIRHHIIHT
301 GEKPYECNEC GKAFNQSSYL TQHQRIHTGE KPYECNECGK AFSQSTFLTQ HQVIHTGEKP
361 YKCNECGKAF SDRSGLIQHQ RTHTGERPYE CNECGKAFGY CSALTQHQRT HTGEKPYKCN
421 DCAKAFSDRS ALIRHQRTHT GEKPYKCKDC GKAFSQSSSL TKHQKTHTGE KPYKCKECGK
481 AFSQSSSLSQ HQKTHAGVKT KKYVQALSEH LTFGQHKRIH TGLocalizationUniProt · AlphaFold · HPA
Whether an antibody against ZNF892 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.49
OntologyGO
Biological processes
Molecular functions
- DNA-binding transcription factor activity, RNA polymerase II-specific
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- zinc ion binding
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads ZNF892 as an antibody target. Whether an autoantibody or antibody against ZNF892 could matter depends on whether native ZNF892 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
ZNF892 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label ZNF892 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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