Seroatlas · Human Serome Atlas

ZNF840P

Zinc finger protein 840

Also known as: ZN840_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NDX5
Gene: ZNF840P
Canonical length: 716 aa

OverviewNCBI Gene

No narrative summary is available for ZNF840P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

716 residues, UniProt reviewed canonical sequence.

>A6NDX5|ZNF840P
     1  MSLMGHGKVE MLLYAVPLLK APNCLSSSMQ LPHGGGRHQE LVRFRDVAVV FSPEEWDHLT
    61  PEQRNLYKDV MLDNCKYLAS LGNWTYKAHV MSSLKQGKEP WMMEREVTGD PCPACQPALA
   121  TFRALNESGN AFRQSFHHGE YRTHRTFVQH YECDDCGMAF GHVSQLTGHQ KIHKVGETHE
   181  YGENTRGFRH RSSFTMLQRI CTLYKHFECN QCGETFNRPS KVIQHQSMHS GLKPYKCDVC
   241  QKAFRFLSSL SIHQRFHVGN RVNLTRHQKT HTQRKPFSCN FCGKTFHRFS EKTQHLLIHT
   301  RKKYYTCNYC KKEFNPYSKF ILHQRTHTGE KPHKCDVCEK SFKSISNLNK HQKTHTGEKP
   361  FSCNECKKTF AQRTDLARHQ QIHTGKKSFI CSSCKKTFVR LSDLTQHKGT HTGERPYQCT
   421  TCEKAFKYRS NFTKHQKTHS IGRPFACNEC GKTYRLNWEL NQHKKIHTGE KPYECGECGK
   481  RFNNNSNLNK HKKIHTGEKH FVCNQCGKAF SLNSKLSRHQ RTHNKKENSS KSVSNLNKHQ
   541  KTHAGEKPFP CNECKKAFAQ RMDLARHQQI HTGRKPFICS SCKKTFVRLS DLTQHKGTHT
   601  GERPYQCTTC EKAFKYQSNF TKHQKTHSIG RPFTCNECGK TFRLNWKLNQ HKKIHTGEKP
   661  YECGECGKCF NNNSNLSKHK KIHTGEKHFV CNQCGKAFSL NSKLSRHQIT HNKKKP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZNF840P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.42

OntologyGO

Biological processes

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZNF840P as an antibody target. Whether an autoantibody or antibody against ZNF840P could matter depends on whether native ZNF840P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZNF840P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZNF840P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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