ZNF705EP
Putative zinc finger protein 705EP
Also known as: Z705E_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for ZNF705EP in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
300 residues, UniProt reviewed canonical sequence.
>A8MWA4|ZNF705EP
1 MHSLKKVTFE DVAIDFTQEE WAMMDTSKRK LYRDVMLENI SHLVSLGYQI SKSYIILQLE
61 QGKELWQEGR EFLQDQNPDR ESALKKTHMI SMHPIIRKDA PTSMTMENSL ILEDPFECND
121 SGEDCTHSST IIQCLLTHSG KKPYVSKQCG KSLSNLLSPK PHKQIHTKGK SYQCNLCEKA
181 YTNCFHLRRP KMTHTGERPY TCHLCRKAFT QCSHLRRHEK THTGERPYKC HQCGKAFIQS
241 FNLRRHERTH LGEKWYECDN SGKAFSQSSG FRGNKIIHTG EKPHACLLCG KAFSLSSDLRLocalizationUniProt · AlphaFold · HPA
Whether an antibody against ZNF705EP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.45
OntologyGO
Biological processes
Molecular functions
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- zinc ion binding
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads ZNF705EP as an antibody target. Whether an autoantibody or antibody against ZNF705EP could matter depends on whether native ZNF705EP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
ZNF705EP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label ZNF705EP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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