Seroatlas · Human Serome Atlas

ZNF542P

Putative zinc finger protein 542

Also known as: ZN542_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q5EBM4
Gene: ZNF542P
Canonical length: 170 aa

OverviewNCBI Gene

No narrative summary is available for ZNF542P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

170 residues, UniProt reviewed canonical sequence.

>Q5EBM4|ZNF542P
     1  MLENYQNLVW LGLSISKSVI SLLEKRKLPW IMAKEEIRGP LPGYFKVSEM TISQEPKAKT
    61  RTLFGKDVPG AEIKELSAKR AINEVLSQFD TVIKCTRNVC KECGNLYCHN MQLTLHKRNH
   121  TQKKCNQCLD CGKYFTRQST LIQHQRIHTG ERPYKCNECI KTFNQRAHLT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZNF542P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.42

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZNF542P as an antibody target. Whether an autoantibody or antibody against ZNF542P could matter depends on whether native ZNF542P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZNF542P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZNF542P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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