ZNF516-DT
Putative uncharacterized protein ZNF516-DT
Also known as: ZNFDT_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for ZNF516-DT in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
163 residues, UniProt reviewed canonical sequence.
>Q6ZTR6|ZNF516-DT
1 MRVPPAGTWA LRPIWTEMGT PLRGSQAPGR IVLLLLVITP QWRWIPSKTP NVAPRSNQRC
61 NPGGYLSGGV SLCASHSQPA ALPNLGRLQK KLLQTRCKGR RMCPKAGDQT GGAFCMCDVS
121 GGGGECVSGS GGGGESGRKT GTTSAMKDPR VLKCKLRVTN DLHLocalizationUniProt · AlphaFold · HPA
Whether an antibody against ZNF516-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.73
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads ZNF516-DT as an antibody target. Whether an autoantibody or antibody against ZNF516-DT could matter depends on whether native ZNF516-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
ZNF516-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label ZNF516-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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