Seroatlas · Human Serome Atlas

ZNF503-AS2

Putative uncharacterized protein encoded by ZNF503-AS2

Also known as: ZNAS2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NEH8
Gene: ZNF503-AS2
Canonical length: 195 aa

OverviewNCBI Gene

No narrative summary is available for ZNF503-AS2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

195 residues, UniProt reviewed canonical sequence.

>A6NEH8|ZNF503-AS2
     1  MGVWGKKHLR LTHAPSPTFS HLPPSPQAGE PGIDGISLAV VCAAFIRIHP ARRHPARNGS
    61  RLACTPTPRP NAGLEVVSSA RVAASLPSEG GWTSGAPRSS GLSLPGSAWQ PPPLPVLRKP
   121  AWPGSPAVKN ESKFPNRGSR NFPRRRLPPA PVSGEPPERC KLAREIRWRL WKAHEGWGGG
   181  AKRPLGDPAW SGVKR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZNF503-AS2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.69

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZNF503-AS2 as an antibody target. Whether an autoantibody or antibody against ZNF503-AS2 could matter depends on whether native ZNF503-AS2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZNF503-AS2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZNF503-AS2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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