Seroatlas · Human Serome Atlas

ZNF355P

Putative zinc finger protein 355P

Also known as: Z355P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9NSJ1
Gene: ZNF355P
Canonical length: 428 aa

OverviewNCBI Gene

No narrative summary is available for ZNF355P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

428 residues, UniProt reviewed canonical sequence.

>Q9NSJ1|ZNF355P
     1  MRDEVAEKEK ADINVTLVFQ GYENTPIMVC VDGIVFSKPD LVTCLEQRKK PWSMKHPGLT
    61  QHNIVHTGDK PYKCKDCGKI FKWSSNLTIH QRIHSGEKPY KCEECGKAFK QSSKLNEHMR
   121  AHTGEKFYKC EECGKAFKHP SGLTLHKRIH TGENPYKFEE CDKAFYWVLS FTKHMIIHRG
   181  EKPYKYQECG KAFKWSSNLT IHKRIHTGEK PCKCEECGKA CKQSLGLTIQ KRIHTEEKPY
   241  KCEECGSSNL TIYKKIHAGE KPYNCEKCGK AFYCSSNLIQ NNIVHAEEKH YKCQECGKAF
   301  KKSLDLNVHK IIHSGEKPYR YEECGKITHS GEESYKCEEC GKGFYCSSSL TKHMIVHTEE
   361  KLYKCEECGK AFKWSSELTI HQRIRTEEKP YKCEECVRVF KHSSKLNEHK RNHTGEKPYK
   421  CEACGKAF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZNF355P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.41

OntologyGO

Biological processes

regulation of transcription by RNA polymerase II

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZNF355P as an antibody target. Whether an autoantibody or antibody against ZNF355P could matter depends on whether native ZNF355P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZNF355P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZNF355P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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