Seroatlas · Human Serome Atlas

WWC2-AS2

Putative uncharacterized protein WWC2-AS2

Also known as: WWAS2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q96NR7
Gene: WWC2-AS2
Canonical length: 200 aa

OverviewNCBI Gene

No narrative summary is available for WWC2-AS2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

200 residues, UniProt reviewed canonical sequence.

>Q96NR7|WWC2-AS2
     1  MTSAETASRA AESGGTPVRP CSRPHRAPSP AAPSRPGAPA AGPRKLLVPG LPCLVRGGWP
    61  WTRPDSSPFR PAARPRMSPH RSPAVARRCG RPRRRDPRRR RTPALPRPWP GRGGPGRSLL
   121  HRHLFIQQLL RTCWPALPRD RTPAPGGTMP GAALAGPGRQ ASGSPAPQSE GAPPRPWTPL
   181  QPGLHHRPPS SSSGLLSSFF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against WWC2-AS2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.73

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads WWC2-AS2 as an antibody target. Whether an autoantibody or antibody against WWC2-AS2 could matter depends on whether native WWC2-AS2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

WWC2-AS2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label WWC2-AS2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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