Seroatlas · Human Serome Atlas

VN1R3

Vomeronasal type-1 receptor 3

Also known as: VN1R3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9BXE9
Gene: VN1R3
Canonical length: 311 aa

OverviewNCBI Gene

No narrative summary is available for VN1R3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

311 residues, UniProt reviewed canonical sequence.

>Q9BXE9|VN1R3
     1  MASKDFAIGM ILLSQIMVGF LGNFFLLYHY SFLCFTRGML QSTDLILKHL TIANSLVILS
    61  KGIPQTMAAF GLKDSLSDIG CKFVFYVHRV GRAVCVGNAC LLSVFQVITI SPSEFRWAEL
   121  KLHAHKYIRS FILVLCWILN TLVNITVLLH VTGKWNSINS TKTNDYGYCS GGSRSRIPHS
   181  LHIVLLSSLD VLCLGLMTLA SGSMVFILHR HKQQVQHIHG TNLSARSSPE SRVTQSILVL
   241  VSTLCYFTRS PPSLHMSLFP NPSWWLLNTS ALITACFPMV SPFVLMSRHP RIPRLGSACC
   301  GRNPQFPKLV R

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against VN1R3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.31

OntologyGO

Biological processes

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads VN1R3 as an antibody target. Whether an autoantibody or antibody against VN1R3 could matter depends on whether native VN1R3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

VN1R3 is annotated at the cell surface, where native VN1R3 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label VN1R3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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