USP17L6P
Ubiquitin carboxyl-terminal hydrolase 17-like protein 6
Also known as: U17L6_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for USP17L6P in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
398 residues, UniProt reviewed canonical sequence.
>Q6QN14|USP17L6P
1 MEDDSLYLRG EWQFNHFSKL TSSRPDAAFA EIQRTSLPEK SPLSCETRVD LCDDLAPVAR
61 QLAPREKLPL SSRRPAAVGA GLQNMGNTCY VNASLQCLTY TPPLANYMLS REHSQTCHRH
121 KGCMLCTMQA HITRALHNPG HVIQPSQALA AGFHRGKQED AHEFLMFTVD AMKKACLPGH
181 KQVDHHSKDT TLIHQIFGGY WRSQIKCLHC HGISDTFDPY LDIALDIQAA QSVQQALEQL
241 VKPEELNGEN AYHCGVCLQR APASKTLTLH TSAKVLILVL KRFSDVTGNK IAKNVQYPEC
301 LDMQPYMSQQ NTGPLVYVLY AVLVHAGWSC HNGHYFSYVK AQEGQWYKMD DAEVTASSIT
361 SVLSQQAYVL FYIQKSEWER HSESVSRGRE PRALGSEDLocalizationUniProt · AlphaFold · HPA
Whether an antibody against USP17L6P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.33
OntologyGO
Biological processes
- protein deubiquitination involved in ubiquitin-dependent protein catabolic process
- regulation of apoptotic process
- regulation of protein stability
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads USP17L6P as an antibody target. Whether an autoantibody or antibody against USP17L6P could matter depends on whether native USP17L6P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
USP17L6P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label USP17L6P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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