Seroatlas · Human Serome Atlas

UBTFL6

Putative upstream-binding factor 1-like protein 6

Also known as: UBFL6_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0CB48
Gene: UBTFL6
Canonical length: 400 aa

OverviewNCBI Gene

No narrative summary is available for UBTFL6 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

400 residues, UniProt reviewed canonical sequence.

>P0CB48|UBTFL6
     1  MPAKDIKVAL PRSQGHWSNA DILRLLECME NNLPYDDNGT FSSTQSHMDW GKVAFKNFSG
    61  EMCRLKWLEI SCSLRKFSTL KKLVLEAKKC VKNTNKSQKG RNHPDFPKRL LTAYIRFFKE
   121  NWPQYSQMYP GMRSQEVTKI LSKKYKELPE QMKQKHIQDF RKEKQEFEEK LARFREEHPD
   181  LDQKGKKSDI CKRVQTKVQK KVQKNIEEVR SLPKTDQFFK KVKFHGEPQK PPMNGYQKFH
   241  QDSWSSKELQ HLSLRERMVE IGRRWQRIPQ SQKDHYKSQA ELLQKEYKVE LDLWLKTLSP
   301  EDYAAYKEST YAKGKNMAMM GGPAPSLKQT DPQSSSAKGL QEGFGEGQGL QAAGTEASQT
   361  IWVNCQVSME PEDNRKKDGE EEESSNSLDC SSGEDMEVDV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against UBTFL6 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.48

OntologyGO

Biological processes

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads UBTFL6 as an antibody target. Whether an autoantibody or antibody against UBTFL6 could matter depends on whether native UBTFL6 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

UBTFL6 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label UBTFL6 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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