Seroatlas · Human Serome Atlas

TTTY12

Putative transcript Y 12 protein

Also known as: TTY12_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q9BZ98
Gene
TTTY12
Canonical length
90 aa

OverviewNCBI Gene

No narrative summary is available for TTTY12 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

90 residues, UniProt reviewed canonical sequence.

>Q9BZ98|TTTY12
     1  MIDPETRHKA FLKAWPWQNS TITFVPGLAI CHYSSVQVPR RGAILPMLYA LCYVKMPSFQ
    61  HGPGRMYHLT CDWPRKMSLS CHVCRAHFRD

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TTTY12 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.49

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TTTY12 as an antibody target. Whether an autoantibody or antibody against TTTY12 could matter depends on whether native TTTY12 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TTTY12 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label TTTY12 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/TTTY12. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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