TRBV6-9
T cell receptor beta variable 6-9
Also known as: TVB69_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- A0A0J9YX75
- Gene
- TRBV6-9
- Canonical length
- 114 aa
- Quaternary structure
- Homodimer
OverviewNCBI Gene
No narrative summary is available for TRBV6-9 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
114 residues, UniProt reviewed canonical sequence.
>A0A0J9YX75|TRBV6-9
1 MSIGLLCCVA FSLLWAGPVN AGVTQTPKFH ILKTGQSMTL QCAQDMNHGY LSWYRQDPGM
61 GLRRIHYSVA AGITDKGEVP DGYNVSRSNT EDFPLRLESA APSQTSVYFC ASSYLocalizationUniProt · AlphaFold · HPA
Whether an antibody against TRBV6-9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 0
OntologyGO
Biological processes
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads TRBV6-9 as an antibody target. Whether an autoantibody or antibody against TRBV6-9 could matter depends on whether native TRBV6-9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
TRBV6-9 is annotated at the cell surface, where native TRBV6-9 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label TRBV6-9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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