Seroatlas · Human Serome Atlas

TPT1P8

Putative translationally-controlled tumor protein-like protein TPT1P8

Also known as: TCTP8_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9HAU6
Gene: TPT1P8
Canonical length: 139 aa

OverviewNCBI Gene

No narrative summary is available for TPT1P8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

139 residues, UniProt reviewed canonical sequence.

>Q9HAU6|TPT1P8
     1  MIIFQDLISH NEMFSDIYKI WEITNGLCLE VEQKMLSKTT GNTDDSLIGR NSSSESTEDE
    61  VTESTIITSV DIVTNHHLQE SIFTKEAYKK YIKDYMKSIN EKLEEQRPER VKLFITGMKN
   121  KSSTSLLIFK TTSSLLVKT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TPT1P8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.4

OntologyGO

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Apoptosis

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TPT1P8 as an antibody target. Whether an autoantibody or antibody against TPT1P8 could matter depends on whether native TPT1P8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TPT1P8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label TPT1P8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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