Seroatlas · Human Serome Atlas

TMA7B

Translation machinery-associated protein 7B

Also known as: TMA7B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A024R1R8
Gene: TMA7B
Canonical length: 64 aa

OverviewNCBI Gene

No narrative summary is available for TMA7B in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

64 residues, UniProt reviewed canonical sequence.

>A0A024R1R8|TMA7B
     1  MSSHEGGKKK ALKQPKKQAK EMDEEEKAFK QKQKEEQKKL EVLKAKVVGK GPLATGGIKK
    61  SGKK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TMA7B can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TMA7B as an antibody target. Whether an autoantibody or antibody against TMA7B could matter depends on whether native TMA7B is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TMA7B is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label TMA7B as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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