TEX48
Testis-expressed protein 48
Also known as: TEX48_HUMAN
Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene
Protein identityUniProt · HPA
- UniProt accession
- A0A1B0GUV7
- Gene
- TEX48
- Ensembl
- ENSG00000230601
- Chromosome
- 9
- Canonical length
- 120 aa
- Protein class
- Predicted intracellular proteins
OverviewNCBI Gene
No narrative summary is available for TEX48 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
120 residues, UniProt reviewed canonical sequence.
>A0A1B0GUV7|TEX48
1 MAAHQNLILK IFCLCCRDCQ EPYAINDSKV PSQTQEHKPS TQNLLLQKDE LDRQNPKRIN
61 AVSHLPSRTP LIQTKKSTSS SSSEFEDLNA YASQRNFYKR NLNRYCQEHW PFQPCLTGRPLocalizationUniProt · AlphaFold · HPA
Whether an antibody against TEX48 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.68
- Highest tissue expression
- 25 nTPM
Expression across tissuesHPA
Tissue
- testis: 25 nTPM
- basal ganglia: 0.1 nTPM
- adipose tissue: 0 nTPM
- adrenal gland: 0 nTPM
- amygdala: 0 nTPM
- appendix: 0 nTPM
Single-cell type
- late spermatids: 1,354 nCPM
- early spermatids: 345 nCPM
- late primary spermatocytes: 178 nCPM
- retinal ganglion cells: 12 nCPM
- adipocytes: 6.2 nCPM
- endometrial stromal cells: 3.3 nCPM
Immune cell
- MAIT T-cell: 0.5 nTPM
- T-reg: 0.2 nTPM
- memory CD8 T-cell: 0.1 nTPM
- plasmacytoid DC: 0.1 nTPM
- basophil: 0 nTPM
- classical monocyte: 0 nTPM
Brain region
- cerebral cortex: 4.5 nTPM
- white matter: 2.7 nTPM
- basal ganglia: 2.3 nTPM
- hippocampal formation: 1.6 nTPM
- medulla oblongata: 1.6 nTPM
- pons: 1.5 nTPM
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads TEX48 as an antibody target. Whether an autoantibody or antibody against TEX48 could matter depends on whether native TEX48 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
TEX48 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label TEX48 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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