Seroatlas · Human Serome Atlas

TEX13D

Testis-expressed protein 13D

Also known as: TX13D_HUMAN

Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A0A0J9YY54
Gene
TEX13D
Ensembl
ENSG00000282419
Chromosome
X
Canonical length
714 aa
Protein class
Predicted intracellular proteins

OverviewNCBI Gene

Predicted to enable mRNA binding activity. [provided by Alliance of Genome Resources, Jul 2025]

Canonical amino-acid sequenceUniProt

714 residues, UniProt reviewed canonical sequence.

>A0A0J9YY54|TEX13D
     1  MAMNFGDHAS GFRHNDVIRF INNEVLMDGS GPAFYVAFRS RPWNEVEDSL QAIVADSQVP
    61  RAIKRACTWS ALALSVRVAT RQREELLHHV RRLQRHAEER QATSWALTSQ LQQLRLEHEV
   121  AATQLHLAQA ALQQALNERD GLYGRLLQIE RFPQAAPLAH EIMSGPQAEQ NGAAACPLAT
   181  EQQSDMVAMG THANAQMPTP TDVLYVPGPL SPWAQGMQPP LPVPHPFPHP PPFPMKFPSL
   241  PPLPPAVVTG AEAAAVPLQM PPTEIHPPCP WPAVGFQEEM APLWYQRSYI QEEDSKILQG
   301  SFPLGDSRSH SQGEGSERSQ RMPLPGDSGC HNPLSESPQG TAPLGSSGCH SQEEGTEGPQ
   361  GMDPLGNRER QNQKEGPKRA RRMHTLVFRR SHKSEGPEGP QGTVPQGDSR SYSQEGCSDR
   421  AQEMATLVFI RRCKPEGPKR PQWTVPLGDS RSHIKEEGPE GPQRIVLQGD NRSYSQEGSP
   481  ERAQGMATLV FSRSCKPEEG PERPQDTPLG DSRSHIKEEG PEGPQRIVLQ GDNRSYSQEG
   541  SPERAQGMAT LVFSRSCKPE EGPERPQDTP LGDSRSHIKE EGPEGPQRIV LQGDNRSYSQ
   601  EGSRERAQGM ATLVFSRSCK PEEGPERPQG TPLGDSRSHG VRESPKKWQP QRQKAKKPKV
   661  NKVSGSQQQE KPASFPVPVN WKCPWCKAIN FSWRTACYKC KKACVPFESG GQTQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TEX13D can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.67
Highest tissue expression
1.7 nTPM

Expression across tissuesHPA

Tissue

  • testis: 1.7 nTPM
  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • amygdala: 0 nTPM
  • appendix: 0 nTPM
  • basal ganglia: 0 nTPM

Single-cell type

  • early primary spermatocytes: 0.5 nCPM
  • early spermatids: 0.4 nCPM
  • differentiating spermatogonia: 0.1 nCPM
  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • white matter: 0.2 nTPM
  • amygdala: 0 nTPM
  • basal ganglia: 0 nTPM
  • cerebellum: 0 nTPM
  • cerebral cortex: 0 nTPM
  • choroid plexus: 0 nTPM

OntologyGO

Molecular functions

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TEX13D as an antibody target. Whether an autoantibody or antibody against TEX13D could matter depends on whether native TEX13D is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TEX13D is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label TEX13D as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/TEX13D. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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