Seroatlas · Human Serome Atlas

TEX13C

Testis-expressed protein 13C

Also known as: TX13C_HUMAN

Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A0J9YWL9
Gene: TEX13C
Ensembl: ENSG00000282815
Chromosome: X
Canonical length: 993 aa
Protein class: Predicted intracellular proteins
Subcellular location: Nucleoplasm,Plasma membrane

OverviewNCBI Gene

Predicted to enable mRNA binding activity. [provided by Alliance of Genome Resources, Jul 2025]

Canonical amino-acid sequenceUniProt

993 residues, UniProt reviewed canonical sequence.

>A0A0J9YWL9|TEX13C
     1  MAMNFGDHAS GFRHDDVIRF INNEVLRNGG SPAFYTAFRS RPWNEVEDRL RAIVADPRVP
    61  RAIKRACTWS ALALSVQVAA RQQEELLYQV WWLQGHVEEC QATSWALTSQ LQQLRLEHEE
   121  VATQLHLTQA ALQQVLNERD GLCGRLLEVE RSMQVYPMPQ DFVPGPEAGQ YGPVAGTLNA
   181  EQSEAVATEA QGMPHSEAQV AAPTAVYYMP EPQSGRVQGM QPLLLMQAPH PVPFHMPSPM
   241  GLPYSTPLPP PVVMESAAAI APQMPPAGIY PPGLWATVGS QEETAPPWDQ KCHGQDGYPE
   301  NFQGVYHPGD NRSCNQKEGS ECPQGMTSQG DSSSHSLKKD PVMQEGTAPP EFSRSHSLEK
   361  KPVMPKEMVP LGDSNSHSLK KDPVVPKEIV PIGDSNSHSL TKNPVVHKEM VSLGDSNSHS
   421  MKKDPVMPQK MVPLGDSNSH SLKKDPMMCQ EMVPLGDSNS HSLKKDPVVA QGTAPLMYSR
   481  RHSQKKVPMM PKEMVPLGES HSHSLKKDLV VPKELVPLGD SKSHRMKKDP VMPQKMVPLG
   541  DSRSHSLKKD PVMPQNMIPL EDSNSHSLKK DPVMPQNMIP LEDSNSHSLK KDPMMHQEMV
   601  PLGDSNSHSL KKDPVVPQDT APLMFSRRHS LKKVPVMPKE MVPLGDSHSL KKDPVMPQNM
   661  VPLEDSNSHS LKKDPVVPQG TAPLMFSRRH SLKKVPVMPK EMVPLGDSNS HSLKKDPVVP
   721  QGTAPLMFSR RHSLKKVPVM PKEMVPLGDS HSLKKDPVMP QNMVPLEDSN SHSLKKDPVV
   781  PQGTAPLTFS RRHSLKKVPV VPQGTASLGF SRIHSLKKEL VMPEEMVPLG DSNSHSMKKD
   841  LVMPKEMVPL GDSNSHSLKK DPVVHQEVVS LGDSNSHSLK KHPVIPQGTA SLRFSKSHSQ
   901  KEDQERPQVT PLEDSKSHGV KNSPWKHQPQ GQKVKEQKRK KASESQQQKP ASCSSPVNWA
   961  CPWCNAMNFP RNKVCSKCKR VRMPVENGSV DPA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TEX13C can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.45
Highest tissue expression: 1.6 nTPM

Expression across tissuesHPA

Tissue

testis: 1.6 nTPM
adipose tissue: 0 nTPM
adrenal gland: 0 nTPM
amygdala: 0 nTPM
appendix: 0 nTPM
basal ganglia: 0 nTPM

Single-cell type

early primary spermatocytes: 11 nCPM
differentiating spermatogonia: 4.9 nCPM
undifferentiated spermatogonia: 1.3 nCPM
late spermatids: 0.3 nCPM
peritubular myoid cells: 0.3 nCPM
early spermatids: 0.1 nCPM

Immune cell

basophil: 0 nTPM
classical monocyte: 0 nTPM
eosinophil: 0 nTPM
gdT-cell: 0 nTPM
intermediate monocyte: 0 nTPM
MAIT T-cell: 0 nTPM

Brain region

basal ganglia: 0.4 nTPM
cerebellum: 0.3 nTPM
cerebral cortex: 0.3 nTPM
hippocampal formation: 0.3 nTPM
white matter: 0.3 nTPM
amygdala: 0.2 nTPM

OntologyGO

Molecular functions

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TEX13C as an antibody target. Whether an autoantibody or antibody against TEX13C could matter depends on whether native TEX13C is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TEX13C is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label TEX13C as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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