Seroatlas · Human Serome Atlas

TAS2R36

Putative taste receptor type 2 member 36

Also known as: T2R36_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0DTE0
Gene: TAS2R36
Canonical length: 309 aa

OverviewNCBI Gene

No narrative summary is available for TAS2R36 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

309 residues, UniProt reviewed canonical sequence.

>P0DTE0|TAS2R36
     1  MICFLLIILS ILVVFAFVLG NFSNGFIALV NVIDWVKRQK ISSADQILTA LVVSRVGLLW
    61  VILLHWYSNV LNSALYSSEV IIFISNAWAI INHFSIWLAT SLSIFYLLKI VNFSRLIFHH
   121  LKRKAKSVVL VIVLGPLVFL VCHLVMKHTY INVWTKEYEG NVTWKIKLRN AIHLSNLTVS
   181  TLANLIPFTL TLISFLLLIY SLCKHLKKMQ LHGKGSQDPS TKVHIKALQT VTSFLLLCAI
   241  YFLSMIISVC NFGRLEKQPV FMFCQAIIFS YPSTHPFILI LGNKKLKQIF LSVFWQMRYW
   301  VKGEKPSSP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TAS2R36 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.32

OntologyGO

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TAS2R36 as an antibody target. Whether an autoantibody or antibody against TAS2R36 could matter depends on whether native TAS2R36 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TAS2R36 is annotated at the cell surface, where native TAS2R36 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label TAS2R36 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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