TAS2R33
Putative taste receptor type 2 member 33
Also known as: T2R33_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for TAS2R33 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
309 residues, UniProt reviewed canonical sequence.
>P0DSN6|TAS2R33
1 MVYFLPIIFS ILVVFAFVLG NFSNGFIALV NVIDWVKRQK ISSADQILTA LVVSRVGLLW
61 VILLHWYANV FNSALYSLEV RIVASNISAV INHFSIWLAA SLSIFYLLKI ANFSNLIFLH
121 LKKRIKSVVL VILLGPLVFL ICNLAVITMD ERVWTKEYEG NVTWKIKLRN AIHLSSLTVT
181 TLANLIPFTL SLICFLLLIC SLCKHLKKMQ LHSKGSQDPS TKVHIKALQT VISFLMLCAI
241 YFLSIMISVW NLRSLENKPV FMFCKAIRFS YPSIHPFILI WGNKKLKQTF LSVFWQVRYW
301 VKGEKPSSPLocalizationUniProt · AlphaFold · HPA
Whether an antibody against TAS2R33 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 7
- Mean surface accessibility (rSASA)
- 0.31
OntologyGO
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads TAS2R33 as an antibody target. Whether an autoantibody or antibody against TAS2R33 could matter depends on whether native TAS2R33 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
TAS2R33 is annotated at the cell surface, where native TAS2R33 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label TAS2R33 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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