Seroatlas · Human Serome Atlas

STRCP1

Putative stereocilin-like protein

Also known as: STRCL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NGW2
Gene: STRCP1
Canonical length: 1772 aa

OverviewNCBI Gene

No narrative summary is available for STRCP1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

1772 residues, UniProt reviewed canonical sequence.

>A6NGW2|STRCP1
     1  MALSLWPLLL LLLLLLLLSF AVTLAPTGPH SLDPGLSFLK SLLSTLDQAP QGSLSRSRFF
    61  TFLANISSSF EPGRMGEGPV GEPPPLQPPA LRLHDFLVTL RGSPDWEPML GLLGDMLALL
   121  GQEQTPRDFL VHQAGVLGGL VEVLLGALVP GGPPTPTQPP CTRDGPSDCV LAADWLPSLL
   181  LLLEGTRWQA LVQVQPSVDP TNATGLDGRE AAPHFLQGLL GLLTPTGELG SKEALWGGLL
   241  RTVGAPLYAA FQEGLLRVTH SLQDEVFSIL GQPEPDTNGQ CQGGNLQQLL LWGVRHNLSW
   301  DVQALGFLSG SPPPPPALLH CLSTGVPLPR ASQPSAHISP RQRRAITVEA LCENHLGPAP
   361  PYSISNFSIH LLCQHTKPAT PQPHPSTTAI CQTAVWYAVS WAPGAQGWLQ ACHDQFPDEF
   421  LDAICSNLSF SALSGSNRRL VKRLCAGLLP PPTSCPEGLP PVPLTPDIFW GCFLENETLW
   481  AERLCGEASL QAVPPSNQAW VQHVCQGPTP DVTASPPCHI GPCGERCPDG GSFLVMVCAN
   541  DTMYEVLVPF WPWLAGQCRI SRGGNDTCFL EGLLGPLLPS LPPLGPSPLC LTPGPFLLGM
   601  LSQLPRCQSS VPALAHPTRL HYLLRLLTFL LGPGAGGAEA QGMLGRALLL SSLPDNCSFW
   661  DAFRPEGRRS VLRTIGEYLE QDEEQPTPSG FEPTVNPSSG ISKMELLACF SPVLWDLLQR
   721  EKSVWALQIL VQAYLHMPPE NLQQLVLSAE REAAQGFLTL MLQGKLQGKL QVPPSEEQAL
   781  GRLTALLLQR YPRLTSQLFI DLSPLIPFLA VSDLMRFPPS LLANDSVLAA IRDYSPGMRP
   841  EQKEALAKRL LAPELFGEVP AWPQELLWAV LPLLPHLPLE NFLQLSPHQI QALEDSWPAA
   901  GLGPGHARHV LRSLVNQSVQ DGEEQVRRLG PLACFLSPEE LQSLVPLSDP TGPVERGLLE
   961  CAANGTLSPE GRVAYELLGV LRSSGGAVLS PRELRVWAPL FSQLGLRFLQ ELSEPQLRAM
  1021  LPVLQGTSVT PAQAVLLLGR LLPRHDLSLE ELCSLHLLLP GLSPQTLQAI PRRVLVGACS
  1081  CLAPELSRLS ACQTAALLQT FRVKDGVKNM GTTGAGPAVC IPGQQPIPTT WPDCLLPLLP
  1141  LKLLQLDSLA LLANRRRYWE LPWSEQQAQF LWKKMQVPTN LTLRNLQALG TLAGGMSCEF
  1201  LQQINSMVDF LEVVHMIYQL PTRVRGSLRA CIWAELQRRM AMPEPEWTTV GPELNGLDSK
  1261  LLLDLPIQLM DRLSNESIML VVELVQRAPE QLLALTPLHQ AALAERALQN LAPKETPVSG
  1321  EVLETLGPLV GFLGTESTRQ IPLQILLSHL SFCLGETFAT ELGWLLLQES VLGKPELWSQ
  1381  DEVEQAGRLV FTLSTEAISL IPREALGPET LERLLEKQQS WEQSRVGQLC RGPQLAAKKA
  1441  ALVAGVVRPA AEDLPEPVPN CADVRGTFPA ACSATQIAEM ELSDFKDCLT LFAGDPGLGP
  1501  EEPRAAMGKA KWLWGPPRGF GPEQILQLGR LLIGLGDQEL QELILVDWGV LSTLGQIDGW
  1561  SSTQLRIVVS SFLRQSGRHV SHLDFVHLTA LGYTLCGLRP EELQHISSWE FSQAALFLGT
  1621  LHLQCSEEQL EFLAHLFVLP GGFGPISNWG PEIFTEIGTI AAGIPDLALS ALLRGQIQGV
  1681  TPLAISVIPP PKFAVVFSPI QLSSLASAQA VAVTPEQMAF LSPEQRRAVA WAQHEGKESP
  1741  EQQGRSTAWG LQDWSRPSWS LVLTISFLGH LL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against STRCP1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.32

OntologyGO

Biological processes

cell-matrix adhesion

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads STRCP1 as an antibody target. Whether an autoantibody or antibody against STRCP1 could matter depends on whether native STRCP1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

STRCP1 is annotated as secreted, so native STRCP1 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label STRCP1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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