Seroatlas · Human Serome Atlas

ST13P4

Putative protein FAM10A4

Also known as: ST134_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8IZP2
Gene: ST13P4
Canonical length: 240 aa

OverviewNCBI Gene

No narrative summary is available for ST13P4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

240 residues, UniProt reviewed canonical sequence.

>Q8IZP2|ST13P4
     1  MDPRKVNELR AFVKMCKKDP SILHTQEMRF LREWVESMGG TATQKAKSEE NTKEEKPDSK
    61  VEEDLKADEP SSEESDLEID KEGVIEPDTD APQEMGDENA EITEEVMDQA NDKKVAAIEA
   121  LNDGELQKAI DLFTDAIKLN PRLAILYAKR ASVFVKLQKP NAAIRDCDRA IEINPDSAQP
   181  YKRRGKAHRL LGHWEEAAHD LALACKFDYD EDASAMLKEV QPRAQKIAEH QRKYERKREE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ST13P4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.37

OntologyGO

Molecular functions

protein dimerization activity

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ST13P4 as an antibody target. Whether an autoantibody or antibody against ST13P4 could matter depends on whether native ST13P4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ST13P4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ST13P4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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