Seroatlas · Human Serome Atlas

SSX6P

Putative protein SSX6

Also known as: SSX6_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q7RTT6
Gene
SSX6P
Canonical length
188 aa

OverviewNCBI Gene

No narrative summary is available for SSX6P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

188 residues, UniProt reviewed canonical sequence.

>Q7RTT6|SSX6P
     1  MNGDDAFAKR PRDDAKASEK RSKAFDDIAK YFSKEEWEKM KFSEKISCVH MKRKYEAMTK
    61  LGFNVTLSLF MRNKRATDSQ RNDSDNDRNR GNEVERPQMT FGRLQRIIPK IMPEKPAEEG
   121  SDSKGVPEAS GPQNDGKKLC PPGKASSSEK IHERSGPKRG KHAWTHRLRE RKQLVIYEEI
   181  SDPEEDDK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SSX6P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Intracellular
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.59

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SSX6P as an antibody target. Whether an autoantibody or antibody against SSX6P could matter depends on whether native SSX6P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SSX6P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SSX6P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/SSX6P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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