Seroatlas · Human Serome Atlas

SSBP3-AS1

Putative uncharacterized protein SSBP3-AS1

Also known as: SSAS1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q7Z2R9
Gene: SSBP3-AS1
Canonical length: 100 aa

OverviewNCBI Gene

No narrative summary is available for SSBP3-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

100 residues, UniProt reviewed canonical sequence.

>Q7Z2R9|SSBP3-AS1
     1  MWGFLVLKAR WLVTPVRTLA TEAGQKPSLR GLLDVGNIQH RAARARGLTR GVIRVSPQER
    61  SQQNQSAPKG PTPSTRPKPR TLGPQAHSLA LQSVDLLFRP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SSBP3-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.64

Genetic constraint and essentialitygnomAD · DepMap

Does the body need this protein intact? Low LOEUF or a strong DepMap dependency means loss or blockade of the protein is likely to be felt.

gnomAD missense Z: 0.32

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SSBP3-AS1 as an antibody target. Whether an autoantibody or antibody against SSBP3-AS1 could matter depends on whether native SSBP3-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SSBP3-AS1 is annotated as secreted, so native SSBP3-AS1 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label SSBP3-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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