Seroatlas · Human Serome Atlas

SPDYE7P

Putative speedy protein E7

Also known as: SPDE7_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q495Y7
Gene: SPDYE7P
Canonical length: 208 aa

OverviewNCBI Gene

No narrative summary is available for SPDYE7P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

208 residues, UniProt reviewed canonical sequence.

>Q495Y7|SPDYE7P
     1  MEWWDKSEES LEEEPRKVLA PEPEEIWVAE MLCGLKMKLK RRRVSLVLPE HHEAFNRLLE
    61  DPVIKRFLAW DKGLRVSDKY LLAMVIVYFS RAGLPSWQYQ CIHFFLALYL ANDMEEDDED
   121  PKQNIFYFLY GKTRSRIPLL RKRRFQLCRC MNPRARKNRS QIVLFQKLRF QFFCSMSCRA
   181  WVSPEELEEI QAYDPEHWVW ARDRARLS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SPDYE7P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.39

OntologyGO

Molecular functions

protein kinase binding

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SPDYE7P as an antibody target. Whether an autoantibody or antibody against SPDYE7P could matter depends on whether native SPDYE7P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SPDYE7P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SPDYE7P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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