Seroatlas · Human Serome Atlas

SNX29P2

Putative protein SNX29P2

Also known as: S29P2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8IUI4
Gene: SNX29P2
Canonical length: 249 aa

OverviewNCBI Gene

No narrative summary is available for SNX29P2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

249 residues, UniProt reviewed canonical sequence.

>Q8IUI4|SNX29P2
     1  MDEERSSMLP TMAAGPNSIL FAINIDNKDL NGQSKFAPTV SDLLKESTQN VTLLKESTQG
    61  VSSVFREITA SSAISILIKP EQETDPLPVV SRNVSADAKC KKERKKKKQV TNIISFDDEE
   121  DEQNSGDMFK KTPGAGESSE DNSDHSSVNI MSAFESPFGP NSNGSQSSNS WKIDSLSLNR
   181  EFGYQKLDVK SIDDEDVDEN EDDVYGNSSG RKHRGHSESP EKNGAHSVTQ AGVQWHDLSS
   241  LQPLPPGFK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SNX29P2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.69

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SNX29P2 as an antibody target. Whether an autoantibody or antibody against SNX29P2 could matter depends on whether native SNX29P2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SNX29P2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SNX29P2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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