Seroatlas · Human Serome Atlas

SNURFL

Putative SNURF-like protein

Also known as: SNUFL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: B1AK76
Gene: SNURFL
Canonical length: 121 aa

OverviewNCBI Gene

No narrative summary is available for SNURFL in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

121 residues, UniProt reviewed canonical sequence.

>B1AK76|SNURFL
     1  MEQARDHLHL RWTTEQHMPE VEVQVKYRTA ALSNQECQLY LRHSQQQQVL VVDFQAKLRQ
    61  VFITETPRCG KKPYWNNEEA ESKQNPGSIY CLLLLIRGGM SDSLIKREIS NFEIVSKNKK
   121  N

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SNURFL can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.46

OntologyGO

Cellular components

nuclear speck

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SNURFL as an antibody target. Whether an autoantibody or antibody against SNURFL could matter depends on whether native SNURFL is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SNURFL is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SNURFL as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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