Seroatlas · Human Serome Atlas

SNRPGP15

Putative small nuclear ribonucleoprotein G-like protein 15

Also known as: RUXGL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MWD9
Gene: SNRPGP15
Canonical length: 76 aa

OverviewNCBI Gene

No narrative summary is available for SNRPGP15 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

76 residues, UniProt reviewed canonical sequence.

>A8MWD9|SNRPGP15
     1  MSKAHPPELK KFTDKKFSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT SGQQKNIGMV
    61  EIRGNSIIML EALERV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SNRPGP15 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.37

OntologyGO

Biological processes

via spliceosome
mRNA splicing

Molecular functions

RNA binding

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SNRPGP15 as an antibody target. Whether an autoantibody or antibody against SNRPGP15 could matter depends on whether native SNRPGP15 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SNRPGP15 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SNRPGP15 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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