SMIM10L3
Small integral membrane protein 10-like protein 3
Also known as: SGSN1_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- A0A0C4DGP1
- Gene
- SMIM10L3
- Canonical length
- 68 aa
OverviewNCBI Gene
No narrative summary is available for SMIM10L3 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
68 residues, UniProt reviewed canonical sequence.
>A0A0C4DGP1|SMIM10L3
1 MAAALSGLAV RLSRSAAARS YGVFCKGLTR TLLIFFDLAW RLRINFPYLY IVASMMLNVR
61 LQVHIEIHLocalizationUniProt · AlphaFold · HPA
Whether an antibody against SMIM10L3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.49
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads SMIM10L3 as an antibody target. Whether an autoantibody or antibody against SMIM10L3 could matter depends on whether native SMIM10L3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
SMIM10L3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label SMIM10L3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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