Seroatlas · Human Serome Atlas

SMAD5-AS1

SMAD5 antisense gene protein 1

Also known as: SMA5O_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9Y6J3
Gene: SMAD5-AS1
Canonical length: 95 aa

OverviewNCBI Gene

No narrative summary is available for SMAD5-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

95 residues, UniProt reviewed canonical sequence.

>Q9Y6J3|SMAD5-AS1
     1  MHKQPKLLPP PATPPPPPQS SSWSGNIVFT IKINIWLRVF SHSSPTGLPK PHSPMPSPPE
    61  PEHSVGKPAN VQIPQVSSPE FCNQKSVLAT EHAQT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SMAD5-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.73

OntologyGO

Biological processes

signal transduction

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SMAD5-AS1 as an antibody target. Whether an autoantibody or antibody against SMAD5-AS1 could matter depends on whether native SMAD5-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SMAD5-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SMAD5-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...