Seroatlas · Human Serome Atlas

SLC67A1-AS

Uncharacterized protein SLC67A1-AS

Also known as: BWR1B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N1D0
Gene: SLC67A1-AS
Canonical length: 253 aa

OverviewNCBI Gene

No narrative summary is available for SLC67A1-AS in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

253 residues, UniProt reviewed canonical sequence.

>Q8N1D0|SLC67A1-AS
     1  MGELPGSEGM WENCPLGWVK KKASGTLAPL DFLLQRKRLW LWASEPVRPQ PQGIHRFREA
    61  RRQFCRMRGS RLTGGRKGFG SSGLRFGRGG FSEEVMPQPV LKAMRCAEGA WWFSPDGPAG
   121  SAASIWPAEG AEGLPGQLGR DRLEVVYSVP DNVPGQNGSR RPLVCKITGK CLSVCSEENA
   181  KAGGCSAFPL LLSQLGARMT GREHAHKGPE LTTPDSGLPR PPNPALAGFR ALAQHSPPLG
   241  TSTPSAVLLS AAT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SLC67A1-AS can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SLC67A1-AS as an antibody target. Whether an autoantibody or antibody against SLC67A1-AS could matter depends on whether native SLC67A1-AS is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SLC67A1-AS is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SLC67A1-AS as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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