Seroatlas · Human Serome Atlas

SCYGR9

Small cysteine and glycine repeat-containing protein 9

Also known as: SCGR9_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0DSO2
Gene: SCYGR9
Canonical length: 92 aa

OverviewNCBI Gene

No narrative summary is available for SCYGR9 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

92 residues, UniProt reviewed canonical sequence.

>P0DSO2|SCYGR9
     1  MGCCGCGSCG CSGGCGGGCG GGCGGGCGSC TTCRCYRVGC CSSCCPCCRG CCGGCCSTPV
    61  ICCCRRTCSS CGCGCGKGCC QQKSCCQKQC CC

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SCYGR9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.51

OntologyGO

Cellular components

intermediate filament

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SCYGR9 as an antibody target. Whether an autoantibody or antibody against SCYGR9 could matter depends on whether native SCYGR9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SCYGR9 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SCYGR9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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