Seroatlas · Human Serome Atlas

SCPPPQ1

Secretory calcium-binding phosphoprotein proline-glutamine rich 1

Also known as: SCPPQ_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A411D538
Gene: SCPPPQ1
Canonical length: 79 aa

OverviewNCBI Gene

No narrative summary is available for SCPPPQ1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

79 residues, UniProt reviewed canonical sequence.

>A0A411D538|SCPPPQ1
     1  MKFLILAGLL STATALPIPL EQYAESSSEQ RFIFYPPQVP PFFPQVLFPL PPQPPLVLTP
    61  NDLIALLIAI LNQLGILFP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SCPPPQ1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.63

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SCPPPQ1 as an antibody target. Whether an autoantibody or antibody against SCPPPQ1 could matter depends on whether native SCPPPQ1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SCPPPQ1 is annotated as secreted, so native SCPPPQ1 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label SCPPPQ1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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