RRP7BP
Putative ribosomal RNA-processing protein 7 homolog B
Also known as: RRP7B_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for RRP7BP in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
103 residues, UniProt reviewed canonical sequence.
>Q9NSQ0|RRP7BP
1 MEAYDQKIAE EEAKAKEEEG VPDEEGWVKV TRRGRRPVLP RTEAASLRVL ERERRKRSQK
61 ELLNYAWQHR ESKMEHLAQL RKKFEEDKQR IELLRAQRKF RPYLocalizationUniProt · AlphaFold · HPA
Whether an antibody against RRP7BP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.53
Cancer expressionTCGA
Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).
OntologyGO
Biological processes
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads RRP7BP as an antibody target. Whether an autoantibody or antibody against RRP7BP could matter depends on whether native RRP7BP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
RRP7BP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label RRP7BP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
Loading the interactive Seroatlas protein explorer...