Seroatlas · Human Serome Atlas

RPLP0P6

Putative ribosomal protein uL10-like

Also known as: RLA0L_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NHW5
Gene: RPLP0P6
Canonical length: 317 aa

OverviewNCBI Gene

No narrative summary is available for RPLP0P6 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

317 residues, UniProt reviewed canonical sequence.

>Q8NHW5|RPLP0P6
     1  MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK VVVLMGKNTM
    61  MRKAIRGHLE NNPALEKLLP HIWGNVGFVF TKEDLTEIRD MLLANKVPAA ARAGAIAPCE
   121  VTVPAQNTGL GPEKTSFFQA LGITTKISRG TIEILSDVQL IKTGDKVGAS EATLLNMLNI
   181  SPFSFGLVIQ QVFDNGSIYN PEVLDKTEET LHSRFLEGVR NVASVCLQTG YPTVASVPHS
   241  IINGYKRVLA LSVETDYTFP LAENVKAFLA DPSAFVAAAP VAADTTAAPA AAAAPAKVEA
   301  KEESEESDED MGFGLFD

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against RPLP0P6 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.4

DiseaseUniProt · ClinVar · IEDB · PubMed

Four sources answering four different questions about RPLP0P6.

Disease | ImmuneIEDB

Conditions an epitope on RPLP0P6 was assayed in.

systemic lupus erythematosus B cell

OntologyGO

Biological processes

Molecular functions

Cellular components

cytosolic large ribosomal subunit

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads RPLP0P6 as an antibody target. Whether an autoantibody or antibody against RPLP0P6 could matter depends on whether native RPLP0P6 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

RPLP0P6 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label RPLP0P6 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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