Seroatlas · Human Serome Atlas

RPL37AP8

Putative ribosomal protein eL43-like

Also known as: RL37L_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NKH3
Gene: RPL37AP8
Canonical length: 93 aa

OverviewNCBI Gene

No narrative summary is available for RPL37AP8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

93 residues, UniProt reviewed canonical sequence.

>A6NKH3|RPL37AP8
     1  MAKCTKKVGG IVSKYRTHHG ASLWKMVKEI EISQHTKYTC SFCGKTKMKR RAVKIRHCNS
    61  CMKTVAGSAW TYNTTSAVMV KSAIRRLKEL KDQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against RPL37AP8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.42

OntologyGO

Biological processes

translation

Molecular functions

Cellular components

cytosolic large ribosomal subunit

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads RPL37AP8 as an antibody target. Whether an autoantibody or antibody against RPL37AP8 could matter depends on whether native RPL37AP8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

RPL37AP8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label RPL37AP8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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