Seroatlas · Human Serome Atlas

RPL13AP3

Putative ribosomal protein uL13-like

Also known as: R13P3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6NVV1
Gene: RPL13AP3
Canonical length: 102 aa

OverviewNCBI Gene

No narrative summary is available for RPL13AP3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

102 residues, UniProt reviewed canonical sequence.

>Q6NVV1|RPL13AP3
     1  MLRHKTKRGH ASLDCLKVFD GIPPPYDKKK RMVVPAALKV VRLKPTRKFA LLGRQAQEVR
    61  WKYQAVTATL EEKRKEKAKI HYWKKKQLMR LRKQAEKNVK KN

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against RPL13AP3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.52

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 6% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

translation

Molecular functions

structural constituent of ribosome

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads RPL13AP3 as an antibody target. Whether an autoantibody or antibody against RPL13AP3 could matter depends on whether native RPL13AP3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

RPL13AP3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label RPL13AP3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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