RIG
Putative protein RIG
Also known as: RIG_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for RIG in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
110 residues, UniProt reviewed canonical sequence.
>Q13278|RIG
1 MPFFSSCLCP SHYSGPSLPS STSSSLPTGP ENQLGFVLLQ AMVHHANSSC VRNAFWLQIT
61 EKLTPALSII ISVVYLRCPE MVENRIGFLL NVKDSKTLSV VGPHPKPCILLocalizationUniProt · AlphaFold · HPA
Whether an antibody against RIG can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.5
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads RIG as an antibody target. Whether an autoantibody or antibody against RIG could matter depends on whether native RIG is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
RIG is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label RIG as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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