Seroatlas · Human Serome Atlas

RIG

Putative protein RIG

Also known as: RIG_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q13278
Gene
RIG
Canonical length
110 aa

OverviewNCBI Gene

No narrative summary is available for RIG in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

110 residues, UniProt reviewed canonical sequence.

>Q13278|RIG
     1  MPFFSSCLCP SHYSGPSLPS STSSSLPTGP ENQLGFVLLQ AMVHHANSSC VRNAFWLQIT
    61  EKLTPALSII ISVVYLRCPE MVENRIGFLL NVKDSKTLSV VGPHPKPCIL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against RIG can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.5

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads RIG as an antibody target. Whether an autoantibody or antibody against RIG could matter depends on whether native RIG is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

RIG is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label RIG as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/RIG. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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