Seroatlas · Human Serome Atlas

Q8TCH9

Putative uncharacterized protein FLJ23865

Also known as: YV004_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8TCH9
Gene: Q8TCH9
Canonical length: 128 aa

OverviewNCBI Gene

No narrative summary is available for Q8TCH9 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

128 residues, UniProt reviewed canonical sequence.

>Q8TCH9|Q8TCH9
     1  MPSTEGFGGL DRLVLPPPPQ VLPLLSPARG RIQFSGRKST GSWVTQMENL LLAQPLPDDC
    61  EILCGWRSLL HLTFLIGFAP HFPHWFCNHH CHQHPPSHLT EVLQSSGELA HQLAPSRCSM
   121  RAEGTHRG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8TCH9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.44

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8TCH9 as an antibody target. Whether an autoantibody or antibody against Q8TCH9 could matter depends on whether native Q8TCH9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8TCH9 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8TCH9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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