Seroatlas · Human Serome Atlas

Q8TAT8

Putative uncharacterized protein LOC644613

Also known as: YK045_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8TAT8
Gene: Q8TAT8
Canonical length: 98 aa

OverviewNCBI Gene

No narrative summary is available for Q8TAT8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

98 residues, UniProt reviewed canonical sequence.

>Q8TAT8|Q8TAT8
     1  MTERRRALSL AAVVDSINLA CVVVSRDWLS LVPAFFYSPP PGGSFSGIKR ESRRKRPSRN
    61  EIYGGGVLEQ EVRMRRWSKT ASPPVSLHHR PLGPARKP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8TAT8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.64

KeywordsUniProt

Signal

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8TAT8 as an antibody target. Whether an autoantibody or antibody against Q8TAT8 could matter depends on whether native Q8TAT8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8TAT8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8TAT8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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