Seroatlas · Human Serome Atlas

Q8NBF4

Putative uncharacterized protein FLJ33307

Also known as: YG006_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NBF4
Gene: Q8NBF4
Canonical length: 154 aa

OverviewNCBI Gene

No narrative summary is available for Q8NBF4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

154 residues, UniProt reviewed canonical sequence.

>Q8NBF4|Q8NBF4
     1  MQLLQVRTTN TLRRLPGTPL MPSAGAVRVV ASVQSGHSWW RMWDGPTGAA EAGSCAEMLR
    61  TSAPGTSRPN LSFLLGQVIP LAHTGSVETL PSEESWGCRQ RASPLPPSTA PMAVSASHRG
   121  GTGTRTWLVD PTLSRDTSPL GGQSWGSPQP SRGA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8NBF4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.46

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8NBF4 as an antibody target. Whether an autoantibody or antibody against Q8NBF4 could matter depends on whether native Q8NBF4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8NBF4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8NBF4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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