Seroatlas · Human Serome Atlas

Q8NAQ8

Putative uncharacterized protein FLJ34945

Also known as: YP023_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NAQ8
Gene: Q8NAQ8
Canonical length: 132 aa

OverviewNCBI Gene

No narrative summary is available for Q8NAQ8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

132 residues, UniProt reviewed canonical sequence.

>Q8NAQ8|Q8NAQ8
     1  MYSVLQLLKC LCSCWRKGPE GRRFQTEAAV CARPAWSPHP AGASEALGAL PPPRQLVEKR
    61  RVSPPRRLDQ SGRDGGAVAK CSLSRGLSPP GWTGRSLLRP WGSAAVLGSR AALACVLRPS
   121  RGVMPATIQS RR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8NAQ8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8NAQ8 as an antibody target. Whether an autoantibody or antibody against Q8NAQ8 could matter depends on whether native Q8NAQ8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8NAQ8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8NAQ8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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