Seroatlas · Human Serome Atlas

Q8N9W7

Putative transmembrane protein FLJ36131

Also known as: YO010_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N9W7
Gene: Q8N9W7
Canonical length: 124 aa

OverviewNCBI Gene

No narrative summary is available for Q8N9W7 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

124 residues, UniProt reviewed canonical sequence.

>Q8N9W7|Q8N9W7
     1  MYVSISFLLG LSHLVLCCLL TFIVNFYLPP ESIDFEFMAH NWSKGRSPSS TLGLSWFKAG
    61  FRFSDGWSMF YSFGLPGVAL PGSPPRSHLL PGTQILIRSF QPCESAKHSA RLSSLLTTTS
   121  YSVS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N9W7 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.47

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N9W7 as an antibody target. Whether an autoantibody or antibody against Q8N9W7 could matter depends on whether native Q8N9W7 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N9W7 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N9W7 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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