Seroatlas · Human Serome Atlas

Q8N9G6

Putative UPF0607 protein FLJ37424

Also known as: YJ012_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8N9G6
Gene
Q8N9G6
Canonical length
341 aa

OverviewNCBI Gene

No narrative summary is available for Q8N9G6 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

341 residues, UniProt reviewed canonical sequence.

>Q8N9G6|Q8N9G6
     1  MRLCLIPRNT GTPQRVLRPV VWSPPSRKKP VLSPHNSIMF GHLSPVRIPC LRGKFNLQLP
    61  SLDDQVIPAR LPKTEVSAEE PKEATEVKDQ VETQGQEDNK RGPCSNGEAA STSRPLETQG
   121  NLTSSWYNPR PLEGNVHLKS LTEKNQTDKA QVHAVSFYSK GHGVASSHSP AGGILPFGKP
   181  DPLPTVLPAP VPGCSLWPEK AALKVLGEDH LPSSPGLLMV GEDMQPKDPA ALGSSRSSPP
   241  RAAGHRSHKR KLSGPPLQLQ PTPPLQLRCD RDERPPPAKL PCLSPEALLV GQASQREGRL
   301  QHGNMRKNMR VLSRISKFRR LRQLLRRRKK TRQGRRGGSC L

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N9G6 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.72

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N9G6 as an antibody target. Whether an autoantibody or antibody against Q8N9G6 could matter depends on whether native Q8N9G6 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N9G6 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N9G6 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q8N9G6. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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