Seroatlas · Human Serome Atlas

Q8N976

Putative uncharacterized protein FLJ38264

Also known as: YG039_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N976
Gene: Q8N976
Canonical length: 141 aa

OverviewNCBI Gene

No narrative summary is available for Q8N976 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

141 residues, UniProt reviewed canonical sequence.

>Q8N976|Q8N976
     1  MISAHCSNLH FLGSSESPTL ASQVGEITGT HHHTRLIFVF LVETGFHHVG HAGLELLTSS
    61  DPPTLASRSA GITGMSHRAR PHGISRGEQV TLGLPLELLE CVSWPLCGSP LRRAQIVSTP
   121  PSPLAALRVP VGAEGWGGTE Q

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N976 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.66

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N976 as an antibody target. Whether an autoantibody or antibody against Q8N976 could matter depends on whether native Q8N976 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N976 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N976 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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